Complementarity of ? opioid ligand pharmacophore and receptor models
نویسندگان
چکیده
منابع مشابه
Complementarity of delta opioid ligand pharmacophore and receptor models.
The elaboration of a pharmacophore model for the delta opioid receptor selective ligand JOM-13 (Tyr-c[D-Cys-Phe-D-Pen]OH) and the parallel, independent development of a structural model of the delta receptor are summarized. Although the backbone conformation of JOM-13's tripeptide cycle is well defined, considerable conformational lability is evident in the Tyr(1) residue and in the Phe(3) side...
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ژورنال
عنوان ژورنال: Biopolymers
سال: 1999
ISSN: 0006-3525,1097-0282
DOI: 10.1002/(sici)1097-0282(1999)51:6<426::aid-bip5>3.0.co;2-g